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Castillo, In a comparative study of transition readiness across chronic conditions, youth with TS had similar health literacy scores, but slightly lower TRAQ scores, compared to peers without a chronic condition Table 7 Musculoskeletal abnormalities. Normally, females have two X chromosomes; however, females with trisomy X carry three X chromosomes in the nuclei of body cells. The optimal estrogen replacement therapy regimen to induce pubertal development is still being evaluated, but, since the previous guidelines 2studies suggest use of transdermal TD preparations as the preferred choice.

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Most studies reported that uterine volume was not affected by the type of estrogen used, but is related to dose and duration of therapysee Fertility section for optimal dosing.

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What is triple X syndrome?

After leaving school, cases seem to feel better. Cardiovascular disease and mortality were considered relevant endpoints. Included studies displayed large heterogeneity with respect to design, included patients, choice of treatment only 3 studies compared oral vs TD E2treatment schedules dose and durationfollow-up duration and reported endpoints. Overcoming non-interoperability of health information between pediatric and adult providers using different EHRs will assist in a seamless transition and a printed rather than digital health summary document may be required. Details of the included studies are shown in Supplementary Fig.

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